• Magnetic Resonance Imaging
• Chemical Exchange Saturation Transfer
• Medical Image Analysis
• Artificial Intelligence

Deputy Editor:

Journal of Magnetic Resonance Imaging

Journal Reviewer:

Magnetic Resonance in Medicine, European Radiology, NMR in Biomedicine, iScience, Comunications Physics, IEEE Transactions on Neural Networks and Learning Systems, IEEE Transactions on Biomedical Engineering, Computer Methods and Programs in Biomedicine, International Journal of Biomedical Imaging, Clinical & Experimental Metastasis, etc.

Conference Reviewer:

Journal Papers

• Huang J, van Zijl PCM, Han X, Dong CM, Cheng GWY, Tse K-H, Knutsson L, Chen L, Lai JHC, Wu EX, Xu J, Chan KWY. Altered d-glucose in brain parenchyma and cerebrospinal fluid of early Alzheimer’s disease detected by dynamic glucose-enhanced MRI. Science Advances, 2020, 6(20): eaba3884.
• Chen L, Schär M, Chan KWY, Huang J, Wei Z, Lu H, Qin Q, Weiss RG, van Zijl PCM, Xu J. In vivo imaging of phosphocreatine with artificial neural networks. Nature Communications, 2020, 11(1): 1-10.
• Su H, Law LH, Liu Y, Huang J*, Chan KWY*. CEST effect of dimethyl sulfoxide at negative offset frequency. NMR in Biomedicine, 2024, 37(12): e5238. (*Corresponding)
• Wang J#, Cai P#, Wang Z, Zhang H, Huang J*. CEST-KAN: Kolmogorov-Arnold Networks for CEST MRI Data Analysis. arXiv preprint arXiv:2406.16026, 2024. (*Corresponding)
• Wang J#, Cai P#, Wang Z, Zhang H, Huang J*. CEST-KAN: Kolmogorov-Arnold Networks for CEST MRI Data Analysis. arXiv preprint arXiv:2406.16026, 2024. (*Corresponding)
• Yang Z, Shen D, Chan KWY, Huang J*. Attention-Based MultiOffset Deep Learning Reconstruction of Chemical Exchange Saturation Transfer (AMO-CEST) MRI. IEEE Journal of Biomedical and Health Informatics, 2024, 28(8): 4636-4647. (*Corresponding)
• Chen Z, Lai JHC, Xu J, Zhang H, Huang J*, Chan KWY*. The effect of aquaporin‐4 inhibition on cerebrospinal fluid‐tissue water exchange in mouse brain detected by magnetization transfer indirect spin labeling MRI. NMR in Biomedicine, 2024, e5093. (*Corresponding)
• Huang J, Lai JHC, Tse K-H, Cheng GWY, Liu Y, Chen Z, Han X, Chen L, Xu J, Chan KWY. Deep neural network based CEST and AREX processing: Application in imaging a model of Alzheimer’s disease at 3 T. Magnetic Resonance in Medicine, 2022, 87(3): 1529-1545. (Editor Picks & MRM Highlights)
• Huang J, Lai JHC, Han X, Chen Z, Xiao P, Liu Y, Chen L, Xu J, Chan KWY. Sensitivity schemes for dynamic glucose-enhanced magnetic resonance imaging to detect glucose uptake and clearance in mouse brain at 3 T. NMR in Biomedicine, 2022, 35(3): e4640. (Cover Article)
• Huang J, Chen Z, Park SW, Lai JHC, Chan KWY. Molecular Imaging of Brain Tumors and Drug Delivery Using CEST MRI: Promises and Challenges. Pharmaceutics, 2022, 14(2): 451.
• Huang J, Xu J, Lai JHC, Chen Z, Lee CY, Mak HKF, Chan KH, Chan KWY. Relayed nuclear Overhauser effect weighted (rNOEw) imaging identifies multiple sclerosis. NeuroImage: Clinical, 2021, 32: 102867.
• Huang J, Han X, Chen L, Xu X, Xu J, Chan KWY. Relayed nuclear Overhauser enhancement imaging with magnetization transfer contrast suppression at 3 T. Magnetic Resonance in Medicine, 2021, 85(1): 254-267.
• Huang J, Chen L, Chan KWY, Cai C, Cai S, Chen Z. Super-resolved water/fat image reconstruction based on single-shot spatiotemporally encoded MRI. Journal of Magnetic Resonance, 2020, 314: 106736.
• Huang J, Zhang M, Lu J, Cai C, Chen L, Cai S. A fast chemical exchange saturation transfer imaging scheme based on single‐shot spatiotemporal encoding. Magnetic Resonance in Medicine, 2017, 77(5): 1786-1796.
• Huang J, Chan KWY. Editorial for “Multi-Parametric MRI for Evaluating Variations in Renal Structure, Function, and Endogenous Metabolites in an Animal Model With Acute Kidney Injury Induced by Ischemia Reperfusion”. Journal of Magnetic Resonance Imaging, 2023. DOI: 10.1002/jmri.29096.
• Huang J, Zhang Y, Chen L, Jiang D, Lin Z. Visualization and assessment of cerebral vasculature, cerebrospinal fluids, and the brain parenchyma in dementia and aging. Frontiers in Aging Neuroscience, 2024, 16: 1443028.
• Leung VWM, Park SW, Lai JHC, Chen Z, Huang J, Liu Y, Hu C, Chan KWY. Imaging treatment efficacy of repeated photodynamic therapy in glioblastoma using chemical exchange transfer saturation MRI. Magnetic Resonance in Medicine, 2024, https://doi.org/10.1002/mrm.30362.
• Chen L#, Xu H#, Gong T, Jin J, Lin L, Zhou Y, Huang J, Chen Z. Accelerating multipool CEST MRI of Parkinson's disease using deep learning-based Z-spectral compressed sensing. Magnetic Resonance in Medicine, 2024, https://doi.org/10.1002/mrm.30233.
• Law LH#, Huang J#, Xiao P, Liu Y, Chen Z, Lai JHC, Han X, Cheng GWY, Tse KH, Chan KWY. Multiple CEST contrast imaging of nose-to-brain drug delivery using iohexol liposomes at 3T MRI. Journal of Controlled Release, 2023, 354, 208-220. (#Contributed equally)
• Chen Z#, Huang J#, Lai JHC, Tse KH, Xu J, Chan KWY. Chemical exchange saturation transfer (CEST) MRI detects myelin changes in cuprizone mouse model at 3T. NMR in Biomedicine, 2023, 10.1002/nbm.4937. (#Contributed equally)
• Wang K, Huang J, Ju L, Xu S, Gullapalli RP, Liang Y, Rogers J, Li Y, van Zijl PCM, Weiss RG, Chan KWY, Xu J. Creatine mapping of the brain at 3T by CEST MRI. Magnetic Resonance in Medicine, 2024, 91(1): 51-60.
• Park SW, Lai JHC, Han X, Leung VWM, Xiao P, Huang J, Chan KWY. Preclinical Application of CEST MRI to Detect Early and Regional Tumor Response to Local Brain Tumor Treatment. Pharmaceutics, 2024, 16(1): 101.
• Mao Z, Chen X, Chen Y, Shen J, Huang J, Chen Y, Duan X, Han Y, Chan KWY, Lu J. A hierarchical salt-rejection strategy for sustainable and high-efficiency solar-driven desalination. Nano Materials Science, 2024, 6(1): 38-43.
• Wang RPH, Huang J, Chan KWY, Leung WK, Goto T, Ho YS, & Chang RCC. IL-1β and TNF-α play an important role in modulating the risk of periodontitis and Alzheimer’s disease. Journal of Neuroinflammation, 2023, 20(1): 1-30.
• Lai J H C, Liu J, Yang T, Huang J, Liu Y, Chen Z, Lee Y, Leung GKK, Chan KWY. Chemical exchange saturation transfer magnetic resonance imaging for longitudinal assessment of intracerebral hemorrhage and deferoxamine treatment at 3T in a mouse model. Stroke, 2023, 54(1): 255-264.
• Xiao P, Huang J, Han X, Cheu JWS, Liu Y, Law LH, Lai JHC, Li J, Park SW, Wong CCL, Lam RHW, Chan KWY. Monitor Tumor pHe and Response Longitudinally during Treatment Using CEST MRI-Detectable Alginate Microbeads. ACS Applied Materials & Interfaces, 2022, 14, 49, 54401–54410.
• Chen X, Wang W, Huang J, Wu J, Chen L, Cai C, Cai S, Chen Z. Ultrafast water–fat separation using deep learning–based single-shot MRI. Magnetic Resonance in Medicine, 2022, 87(6): 2811-2825.
• Han Z, Chen C, Xu X, Bai R, Staedtke V, Huang J, Chan KWY, Xu J, Kamson DO, Wen Z, Knutsson L, van Zijl PCM, Liu G. Dynamic contrast-enhanced CEST MRI using a low molecular weight dextran. NMR in Biomedcine, 2022, 35(3): e4649.
• Sui R, Chen L, Li Y, Huang J, Chan KWY, Xu X, van Zijl PCM, Xu J. Whole‐brain amide CEST imaging at 3T with a steady‐state radial MRI acquisition. Magnetic Resonance in Medicine, 2021, 86(2): 893-906.
• Chen L, Wei Z, Chan KWY, Li Y, Suchal K, Bi S, Huang J, Xu X, Wong PC, Lu H, van Zijl PCM, Li T, Xu J. D-Glucose uptake and clearance in the tauopathy Alzheimer’s disease mouse brain detected by on-resonance variable delay multiple pulse MRI. Journal of Cerebral Blood Flow & Metabolism, 2021, 41(5): 1013-1025.
• Han X, Lai JHC, Huang J, Park SW, Liu Y, Chan KWY. Imaging self-healing hydrogels and chemotherapeutics using CEST MRI at 3 T. ACS Applied Bio Materials, 2021, 4(7): 5605-5616.
• Han X, Huang J, To AK, Lai JHC, Xiao P, Wu EX, Xu J, Chan KWY. CEST MRI detectable liposomal hydrogels for multiparametric monitoring in the brain at 3T. Theranostics, 2020, 10(5): 2215.
• Mao Z, Zhu K, Pan L, Liu G, Tang T, He Y, Huang J, Hu J, Chan KWY, Lu J. Direct‐Ink Written Shape‐Morphing Film with Rapid and Programmable Multimotion. Advanced Materials Technologies, 2020, 5(2): 1900974.
• Liu Y, Lv X, Liu H, Zhou Z, Huang J, Lei S, Cai S, Chen Z, Guo Y, Chen Z, Zhou X, Nie L. Porous gold nanocluster-decorated manganese monoxide nanocomposites for microenvironment-activatable MR/photoacoustic/CT tumor imaging. Nanoscale, 2018, 10(8): 3631-3638.
• Cheng Y, Zhang S, Kang N, Huang J, Lv X, Wen K, Ye S, Chen Z, Zhou X, Ren L. Polydopamine-coated manganese carbonate nanoparticles for amplified magnetic resonance imaging-guided photothermal therapy. ACS Applied Materials & Interfaces, 2017, 9(22): 19296-19306.
• Chen L, Huang J, Zhang T, Li J, Cai C, Cai S. Variable density sampling and non-Cartesian super-resolved reconstruction for spatiotemporally encoded single-shot MRI. Journal of Magnetic Resonance, 2016, 272: 1-9.
• Zhang T, Chen L, Huang J, Li J, Cai S, Cai C, Chen Z. Ultrafast multi-slice spatiotemporally encoded MRI with slice-selective dimension segmented. Journal of Magnetic Resonance, 2016, 269: 138-145.

Conference Proceedings

• Huang J, Park SW, Chan KWY. Evaluating the effectiveness of distortion self-correction for CEST-EPI. ISMRM, Singapore, 2024, Digital Poster, No.2536.
• Huang J, Lin Y, Cao P, Lee CW, Wang Z, Cai P, Lee CY, Bae KT, Mak HKF, Chan KWY, Chan KH. Imaging the brain with multiple sclerosis using 3D CUBE CEST MRI at clinical 3T. ISMRM, Singapore, 2024, Digital Poster, No.2526.
• Huang J, Lai JHC, Han X, Chen Z, Liu Y, Xiao P, Chen L, Xu J, Chan KWY. Sensitive imaging schemes for dynamic glucose enhanced (DGE) MRI to detect glucose uptake and clearance in mouse brain at 3T. ISMRM & SMRT, 2021, Oral Session, No.0433. Summa Cum Laude.
• Huang J, Xu J, Lai JHC, Mak HKF, Chan KH, Chan KWY. Relayed nuclear Overhauser effect (rNOE) imaging identifies multiple sclerosis: an initial human study. ISMRM & SMRT, 2021, Oral Session, No.0492.
• Huang J, Lai JHC, Tse K-H, Cheng GWY, Han X, Liu Y, Chen Z, Chen L, Xu J, Chan KWY. CEST and AREX data processing based on deep neural network: application to image Alzheimer’s disease at 3T. ISMRM & SMRT, 2021, Digital Poster, No.3707.
• Chen Z^#, Huang J^#, Liu Y, Lai JH, Chan KWY. DGE-MRI detects the therapeutic effect of IL-33 in Alzheimer’s mice by assessing cerebral glucose uptake and clearance at 3T. ISMRM & SMRT, 2021, Digital Poster, No.1938. ^#Equally contributed.
• Huang J, Han X, Dong CM, Cheng GWY, Tse K-H, Chen L, Lai JHC, Wu EX, van Zijl PCM, Xu J, Chan KWY. Dynamic glucose enhanced (DGE) MRI at 3T detects alterations in glucose uptake and clearance in young and old Alzheimer’s mice. ISMRM & SMRT, 2020, Oral Session, No.0212. Magna Cum Laude.
• Huang J, Han X, Chen L, Xu X, van Zijl PCM, Xu J, Chan KWY. Magnetization transfer contrast (MTC) suppressed relayed nuclear Overhauser enhancement (rNOE) imaging at 3 T. ISMRM & SMRT, 2020, Digital Poster, No.3141.
• Lai JHC^#, Huang J^#, Han X, Xu J, Chan KWY. Alzheimer’s Disease identification by an artificial neutral network based on chemical exchange saturation transfer (ANNCEST) MRI. ISMRM & SMRT, 2020, Digital Poster, No.3123. ^#Equally contributed.
• Huang J, Xu J, Dong CM, Chen L, Han X, Wu EX, van Zijl PCM, Chan KWY. Impaired glucose uptake in mouse brain with Alzheimer's disease detected by dynamic glucose enhanced (DGE) MRI at 3T. Alzheimer's Association International Conference, LA, USA, 2019, 15, 747.
• Huang J, Xu J, Dong CM, Chen L, Han X, Wu EX, Van Zijl PCM, Chan KWY. Dynamic glucoCEST MRI detects regional changes in cerebral glucose uptake in Alzheimer’s disease at 3T. ISMRM 27th Annual Meeting & Exhibition, Montréal, Canada, 2019, Oral Session, No.0626.
• Huang J, Zhang M, Cai S, Cai C, Chen L, Zhang T. A fast chemical exchange saturation transfer imaging scheme based on spatiotemporal encoding. ISMRM 24th Annual Meeting & Exhibition, Digital Poster, Singapore, 2016, No.2911.