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Dr. Elaine Yuen-Phin Lee



Dr Lee

Clinical Associate Professor, Department of Diagnostic Radiology, HKU

  • BMedSci, BMBS (Notts, UK), MD (HKU, HK), FRCR (UK)
email eyplee77@hku.hk
email HKU Scholar Hub
Research Interests
  • Gynaecological oncology imaging, in particular, applications of functional modalities including PET/CT and diffusion-weighted MRI.
  • Diffusion-weighted MRI in body imaging.
  • General thoracic imaging.
Selected Publications
GYNAECOLOGY

  • Perucho JAU, Wang M, Vardhanabhuti V, Tse KY, Chan KKL, Lee EYP. Association between IVIM parameters and treatment response in locally advanced squamous cell cervical cancer treated by chemoradiotherapy. Eur Radiol. 2021 Mar 30. 
    PMID: 33786654
    https://doi.org/10.1007/s00330-021-07817-w

  • An H, Wang YA, Wong EMF, LV SS, Han LJ, Peng C, Lee EYP. CT texture analysis in histological classification of epithelial ovarian carcinoma. Eur Radiol. 2021 Jan 6.
    PMID: 33409777 
    https://doi.org/10.1007/s00330-020-07565-3

  • Perucho JAU, Wang M, Tse KY, Ip P, Siu SWK, Ngan HYS, Khong PL, Lee EYP. Association between MRI histogram features and treatment response in locally advanced cervical cancer treated by chemoradiotherapy. Eur Radiol. 2020 Sep 3.
    PMID: 32885298
    https://doi.org/10.1007/s00330-020-07217-6

  • Tsoi TT, Chiu KWH, Chu MMY, Ngan HYS, Lee EYP. Metabolic active peritoneal sites affect tumor debulking in ovarian and peritoneal cancers. J Ovarian Res. 2020 May; 13(1):61.
    PMID: 32434520
    https://doi.org/10.1186/s13048-020-00662-3

  • Wang M, Perucho JAU, Tse KY, Chu MMY, Ip P, Lee EYP. MRI Texture Features Differentiate Clinicopathological Characteristics of Cervical Carcinoma. Eur Radiol. 2020 May 7; 30(10): 5384-91.
    PMID: 32382845
    https://doi.org/10.1007/s00330-020-06913-7

  • Lee EYP, An H, Perucho JAU, Chiu K, Hui E, Chu M, Ngan HYS. Functional tumour burden of peritoneal carcinomatosis derived from DWI could predict incomplete tumour debulking in advanced ovarian carcinoma. Eur Radiol. 2020 May 13; 30(10): 5551-9.
    PMID: 32405751
    https://doi.org/10.1007/s00330-020-06887-6

  • Perucho JAU, Chiu KWH, Wong EMF, Tse KY, Chu MMY, Chan Q, Chan LWC, Pang H, PL Khong, Lee EYP. Diffusion-weighted magnetic resonance imaging of primary cervical cancer in the detection of sub-centimetre metastatic lymph nodes. Cancer Imaging 2020 April 6: 20:1-9.
    PMID: 32252829
    https://doi.org/10.1186/s40644-020-00303-4

  • Lee EYP, An H, Tse KY, Khong PL. Molecular imaging of peritoneal carcinomatosis in ovarian cancer. AJR Am J Roentgenol. 2020 Jun; 215(2): 305-12.
    PMID: 32551907
    https://doi.org/10.2214/AJR.19.22621

  • An H, Chiu KWH, Tse KY, Ngan HYS, Khong PL, Lee EYP. The value of contrast-enhanced CT in the detection of residual disease after neo-adjuvant chemotherapy in ovarian cancer. Acad Radiol 2020 Jul;27(7):951-957.
    PMID: 31629627
    https://doi.org/10.1016/j.acra.2019.09.019

  • An H, Ma XD, Pan ZY, Guo H, Lee EYP. Qualitative and quantitative comparison of image quality between single-shot echo-planar and interleaved multi-shot echo-planar diffusion-weighted imaging in female pelvis. Eur Radiol. 2020 Apr; 30(4):1876-84.
    PMID: 31822971
    https://doi.org/10.1007/s00330-019-06491-3

  • Perucho JAU, Chang CHC, Vardhanabhuti V, Wang M, Becker AS, Wurnig MC, Lee EYP. B-value optimization in the estimation of intravoxel incoherent motion parameters in patients with cervical cancer. Korean J Radiol. 2020 Jan; 21(2): 218-27.
    PMID: 31997597
    https://doi.org/10.3348/kjr.2019.0232

  • Wang M, Perucho JAU, Chan Q, Sun J, Ip P, Tse KY, Lee EYP.  Diffusion kurtosis imaging in the assessment of cervical carcinoma. Acad Radiol. 2019 Jul 16; 27(5):e94-e101.
    PMID: 31324577
    https://doi.org/10.1016/j.acra.2019.06.022

  • An H, Lee EYP, Chiu K, Chang C. The emerging roles of functional imaging in ovarian cancer with peritoneal carcinomatosis. Clin Radiol. 2018 Jul; 73(7):597-609.
    PMID: 29685803
    https://doi.org/10.1016/j.crad.2018.03.009

  • Lai AYT, Perucho JAU, Xu X, Hui ES, Lee EYP. Concordance of FDG PET/CT metabolic tumour volume versus DW-MRI functional tumour volume with T2-weighted anatomical tumour volume in cervical cancer. BMC Cancer. 2017 Dec; 17(1):825.
    PMID: 29207964
    https://doi.org/10.1186/s12885-017-3800-9

  • Lee EYP, Perucho JA, Vardhanabhuti V, He J, Siu SW, Ngu SF, Mayr NA, Yuh WTC, Chan Q, Khong PL. Intravoxel incoherent motion MRI assessment of chemoradiation-induced pelvic bone marrow changes in cervical cancer and correlation with hematological toxicity. J Magn Reson Imaging. 2017 Nov; 46(5):1491-8.
    PMID: 28225579
    https://doi.org/10.1002/jmri.25680

  • Becker AS, Ghafoor S, Marcon M, Perucho JA, Wurnig MC, Wagner MW, Khong PL, Lee EYP, Boss A. MRI texture features may predict differentiation and nodal stage of cervical cancer: a pilot study. Acta Radiol Open. 2017 Oct 17; 6(10):2058460117729574.
    PMID: 29085671
    https://doi.org/10.1177/2058460117729574
    (SJR 0.124, Rank 276/328; citations 27)

  • Becker AS, Perucho JA, Wurnig MC, Boss A, Ghafoor S, Khong PL, Lee EYP. Assessment of cervical cancer with a parameter-free intravoxel incoherent motion imaging algorithm. Korean J Radiol. 2017 May-Jun; 18(3):510-8.
    PMID: 28458603
    https://doi.org/10.3348/kjr.2017.18.3.510

  • Agarwal Sharma R, Lee EYP, Vardhanabhuti V, Khong PL, Ngu SF. Unusual case of postmenopausal diffuse endometriosis mimicking metastatic ovarian malignancy. Clin Nucl Med. 2016 Feb; 41(2): e120-2.
    PMID: 26462045
    https://doi.org/ 10.1097/RLU.0000000000001038

  • Lee EYP, Hui ES, Chan KK, Tse KY, Kwong WK, Chang TY, Chan Q, Khong PL. Relationship between intravoxel incoherent motion diffusion-weighted MRI and dynamic contrast-enhanced MRI in tissue perfusion of cervical cancers. J Magn Reson Imaging.  2015 Aug; 42(2):454-9.
    PMID: 25413245
    https://doi.org/10.1002/jmri.24808

  • Lee EYP, Yu X, Chu MM, Ngan HY, Siu SW, Soong IS, Chan Q, Khong PL. Perfusion and diffusion characteristics of cervical cancer based on intravoxel incoherent motion MR imaging-a pilot study. Eur Radiol. 2014 Jul; 24(7):1506-13.
    PMID: 24744198
    https://doi.org/10.1007/s00330-014-3160-7

  • Yu X, Lee EYP, Lai V, Chan Q. Correlation between tissue metabolism and cellularity assessed by standardized uptake value and apparent diffusion coefficient in peritoneal metastasis. J Magn Reson Imaging. 2014 Jul; 40(1):99-105.
    PMID: 24170710
    https://doi.org/10.1002/jmri.24361

  • Lee EYP, Khong PL, Tse KY, Chan KK, Chu MM, Ngan HY. Differentiation of aggressive and indolent subtypes of uterine sarcoma using maximum standardized uptake value. Nucl Med Commun. 2013 Dec; 34(12):1185-9.
    PMID: 24100443
    https://doi.org/ 10.1097/MNM.0000000000000005

THORACIC

  • Lee EYP, Ng MY. Khong PL. COVID-19 pneumonia: what has CT taught us? (Invited comment) Lancet Infectious Diseases. 2020 Apr; 20(4):384-5.
    PMID: 32105641
    https://doi.org/ 10.1016/S1473-3099(20)30134-1

  • Wong HYF, Lam Lam, Fong AHT, Leung ST, Chin TWY, Lo CSY, Lui MMS, Lee JCY, Chiu KWH, Chung T, Lee EYP, Wan EYF, Hung FNI, Lam TPW, Kuo M, Ng MY. Frequency and Distribution of Chest Radiographic Findings in COVID-19 Positive Patients. Radiology 2020 Mar; 296(2):E72-E78.
    PMID: 32216717
    http://doi.org/10.1148/radiol.2020201160

  • Ng MY, Lee EYP, Yang J, Yang FF, Li X, Wang HX, Lui MMS, Lo CSY, Leung B, Ng WKC, Lee YC, Khong PL, Hui CKM, Yuen KY, Kuo MD. Imaging Profile of the COVID-19 Infection: Radiologic Findings and Literature Review. Radiol Cardiothorac Imaging 2020 Feb 13; 2(1):e200034.
    PMID: 33778547
    https:/doi.org/10.1148/ryct.2020200034
    (non-indexed, citations 285)

  • Lee VH, Chan WW, Lee EYP, Choy TS, Ho PP, Leung DK, et al. Prognostic significance of standardized uptake value of lymph nodes on survival for stage III non-small cell lung cancer treated with definitive concurrent chemoradiotherapy. Am J Clin Oncol. 2016 Aug; 39(4):355-62.
    PMID: 24710123
    https://doi.org/ 10.1097/COC.0000000000000070

  • Lee EYP, Khong PL, Lee VH, Qian W, Yu X, Wong MP. Metabolic phenotype of stage IV lung adenocarcinoma: relationship with epidermal growth factor receptor mutation. Clin Nucl Med. 2015 Mar; 40(3):e190-5.
    PMID: 25608155
    https://doi.org/ 10.1097/RLU.0000000000000684

  • Lee EYP, Wong CS, Fung SL, Yan PK, Ho JC. SUV as an adjunct in evaluating disease activity in idiopathic pulmonary fibrosis - a pilot study. Nucl Med Commun. 2014 Jun; 35(6):631-7.
    PMID: 24472818
    https://doi.org/ 10.1097/MNM.0000000000000083

  • Lee EYP, Khong PL. The value of 18F-FDG PET/contrast-enhanced CT in detection of tumor thrombus. Clin Nucl Med. 2013 Feb; 38(2):e60-5.
    PMID: 23334142
    https://doi.org/10.1097/RLU.0b013e318266d53e

EDUCATION

  • Coiffier B, See C, Lee EYP, Chen J, Chiu KWH, Khong PL. Exploring the experience of medical students as peer teachers in clinical ultrasonography: why do they do it and how do they perform? MedEdPublish 2019 Oct.
    https://doi.org/10.15694/mep.2019.000192.1

  • Coiffier B, Shen PCH, Lee EYP, Kwong TSP, Lai AYT, Wong EMF, Chiu KWH, Vardhanabhuti V, Khong PL. Introducing point-of-care ultrasound through structured multifaceted ultrasound module in the undergraduate medical curriculum at the University of Hong Kong. Ultrasound 28(1), 38–46.
    PMID: 32063993
    https://doi.org/10.1177/1742271X19847224

BOLD: Corresponding author